For the grape lover in your house...

(Alternative title #1: Better than a free parade!!!)
(Alternative title #2: Don't worry, "sigmoidoscopy" is the name of that little hammer they hit your knee with.)

Volunteers Needed for Grape Cancer Prevention Study

Healthy adult volunteers are being sought to participate in a study
that will examine whether a diet supplemented with grapes can help
prevention colon cancer. The study is directed by Dr. Randall
Holcombe and is designed to see whether a component in grapes,
resveratrol, acts to block a key signaling pathway involved in the
development of colon cancer.

Participants will be placed on a monitored diet for 2 weeks which
avoids foods rich in resveratrol. They will then have a limited
flexible sigmoidoscopy to get a biopsy of the lining of the colon.
Then, participants will have their diet supplemented each day with
fresh grapes, between 1/3 of a pound and 1 pound per day for 2 weeks
and have the biopsy procedure repeated.

There will be no cost to participants. Each participant will receive
$100, vouchers from Ralphs to assist in the purchase of grapes, a
digital kitchen scale and cooler bag. This study is approved by the
UCI Institutional Review Board. For more information, please call
study coordinator Micii Martinez at 714-456-7069.


Randall F. Holcombe, MD
Director, Office of Clinical Research and Trials